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Genetic Findings in Mice May Point to Autism's Roots.(Brief article)
- Article from:
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Genomics and Proteomics
- Article date:
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June 1, 2006
- Author:
- Ritsma, Rich
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Copyright informationCOPYRIGHT 2006 Advantage Business Media. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Rich Ritsma
Researchers at UT Southwestern Medical Center, Dallas, found that deleting a gene in a certain part of the brain causes mice to exhibit social interaction deficiencies reminiscent of humans with autism spectrum disorders. They also found physical abnormalities in the brains that mimic some cases of autism.
The researchers focused on a gene called Pten. While some people with autism have mutations in Pten, it has been unclear if that is an actual cause of the disease. To test the hypothesis, the researchers ...
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Autism's DNA trail: gene variant tied to developmental disorder.
Science News;
October 21, 2006 ;
Bower, B.;
539 words
......genetic roots of autism. Inheritance of a common variant of a gene that influences...moderate-to-high-risk autism-vulnerability gene, reports developmental...identified a candidate gene for autism, replicated their...demonstrated that gene's biological function...
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Gene link to autism raises treatment hopes
The Scotsman;
January 11, 2008 ;
Lyndsay Moss;
386 words
......variant in the CNTNAP2 gene. A larger study...295 children with autism and their healthy...also identified the gene variant and the link with autism. It found the gene was most active in...researchers, said: "This gene not only may predispose children to autism, it may also ...
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Researchers: Autism may depend on genetic imprinting
University Wire;
October 23, 2000 ;
Matt Brumm;
432 words
......responsible for autism. "Now you know what kind of gene you're looking...And finding the gene will allow scientists...characteristics of autism. "(Diagnosis) is...disease-causing gene. Duke researchers...genetic linkage to autism in addition to...
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Damaged gene linked to autism risk.
Newsday (Melville, NY);
October 18, 2006 ;
402 words
......Jamie Talan Oct. 18--A gene known for its role in...a person's risk for autism, according to a new...genome of patients with autism. The MET gene comes in several varieties...This is not the first gene linked to autism, but genetic studies...
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AUTISM RISK HIGHER IN PEOPLE WITH GENE VARIANT
US Fed News Service, Including US State News;
January 10, 2008 ;
787 words
......found a variation in a gene that may raise the risk of developing autism, especially when the...studies have implicated the gene in autism, and in this study researchers...an excellent candidate gene for autism," Chakravarti said...
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Risky DNA: autism studies yield fresh genetic leads.(This...
Science News;
January 12, 2008 ;
Bower, Bruce;
588 words
......of copies of each gene in the genomes of...children diagnosed with autism or a related disorder...of a brain-related gene ups the chances that a child will develop autism. A team led by geneticist...that children with autism tended to inherit a specific version of a gene within that ...
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LARGEST GENOMIC SEARCH FINDS GENES THAT MAY CONTRIBUTE TO AUTISM
US Fed News Service, Including US State News;
February 18, 2007 ;
787 words
......to-be-pinpointed gene on chromosome 11...susceptibility genes for autism. "Neurexin 1 is a...previously implicated in autism. The new finding suggests that the gene is potentially important in autism. "As for the chromosome...with a history of autism. Researchers used so-called ...
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Fed: Gene discovery could one day lead to cure for autism
AAP General News (Australia);
September 25, 2003 ;
362 words
......Australia) 09-25-2003 Fed: Gene discovery could one day lead to cure for autism By Rosemary Desmond BRISBANE...researcher has made a world first gene discovery which could one...cure for the mental disorder autism. Dr Daniel Markovich, a senior...Queensland, has isolated a gene known as ...
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Autism study looks at gene that helps link brain cells
The Record (Bergen County, NJ);
March 20, 2008 ;
DELTHIA RICKS, SPECIAL FROM NEWSDAY;
423 words
......NJ) 03-20-2008 Autism study looks at gene that helps link...to 2 percent of autism cases may be directly...malfunctions in this gene. "What we know about...dimension. The latest gene discovery involved...92 patients with autism from 81 families...
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Scientists identify gene involved in autism.(News)
The Journal (Newcastle, England);
April 2, 2004 ;
292 words
...A gene that may increase the risk of autism in the general population...suspect that a number of gene mutations play a role in autism. Several studies have pointed...families with a history of autism. Mutations in one gene occurred with greater frequency...
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Gene Variant Carries Increased Risk of Autism.
Ascribe Higher Education News Service;
October 16, 2006 ;
761 words
......associated with the MET gene is common in children with autism and appears more frequently...development is disrupted in autism. This gene also happens to be located...Levitt wondered if this gene could be involved in autism vulnerability. In the...
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Scientists Advance Understanding of the Role of a Key Brain Protein in...
PR Newswire;
July 18, 2005 ;
787 words
......of PRKCB1 With Autism Published Scientists...variations in the gene for protein kinase...Haplotypes in the gene encoding protein...associated with autism. Mol Psychiatry...within the PRKCB1 gene are strongly associated with autism. An independent...
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U.S. Researchers Find Gene Possibly Linked to Autism
Xinhua News Agency;
November 29, 2000 ;
265 words
......people to developing autism, because the gene, called XOHA1, plays...copies of the HOXA1 gene. When the researchers...relatives of the autism patients, they found...one copy of the gene variant, a statistically...one patient with autism and none of the...
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Autism leads.(SCOPE'S SCOOPS)
Science Scope;
February 1, 2008 ;
426 words
......of copies of each gene in the genomes of...children diagnosed with autism or a related disorder...of a brain-related gene ups the chances that a child will develop autism. A team led by geneticist...that children with autism tended to inherit a specific version of a gene within that ...
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Autism gene identification by global research consortium underway
The Hindustan Times;
March 14, 2007 ;
324 words
......help in identifying autism propensity genes. The consortium used "gene chip" technology...earlier linked to autism. They also found a gene on chromosome 11...be associated with autism vulnerability. That gene has not yet been...
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