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Researchers Find Protein Critical to Gene Silencing.(Brief article)
- Article from:
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Genomics and Proteomics
- Article date:
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June 1, 2006
- Author:
- Ritsma, Rich
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Copyright informationCOPYRIGHT 2006 Advantage Business Media. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Rich Ritsma
Studying nucleolar dominance, in which one parental set of ribosomal genes in a hybrid is silenced, researchers at Washington University, St. Louis, Mo., discovered a protein that plays an important role in turning off thousands nearly identical genes in a hybrid plant.
The team identified the protein HDA6 as a crucial component in the silencing. Using the experimental plant genus Arabidopsis , they have shown that HDA6 is located in the nucleus of the plant's cells, imaged it, characterized it biochemically, and defined its role in two cellular activities that ...