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Article: Newsday, Melville, N.Y., Animal House column.
- Article from:
- Newsday (Melville, NY)
- Article date:
- July 10, 2006
CopyrightCOPYRIGHT 2006 Newsday. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Byline: Denise Flaim
Jul. 10--It's not just ivermectin anymore. Most dog-savvy people -- not to mention their vets -- know about the connection between collies and invermectin. These herding dogs have a heritable sensitivity to the anti-parasitic drug, which can overwhelm the blood-brain barrier, causing neurotoxicity, coma and, sometimes, death. In 2001, veterinarian Katrina Mealey of Washington State University College of Veterinary Medicine in Pullman, Wash., and her team found that ivermectin sensitivity is caused by a mutation in the multi-drug resistance gene (MDR1), which controls a protein that helps pump drugs and toxins out of the brain.
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