Article: Anxiety in bipolar disorder: data on cotreatment are lacking, but anecdotally, antimanics and antipsychotics have proven useful.(PRACTICAL PSYCHOPHARMACOLOGY)(Systematic Treatment Enhancement Program for Bipolar Disorder)

Until recently, discussions of bipolar comorbidity centered on substance abuse. It is now recognized, however, that anxiety is at least as prevalent in bipolar patients and has a substantial negative effect on the course of the mood disorder.

Analysis of data from the first 500 participants in the multicenter Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) found that more than half had a lifetime history of an anxiety disorder, that current prevalence was nearly one-third, and that rates were higher for bipolar I than II. Figures reported elsewhere have been even higher. The presence of comorbid anxiety was associated with lower rates of ...

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