Article: Anti-inflammatory properties of narrow-band blue light.

Abstract

Background: Narrow-band blue light (420 nm) has demonstrated safety and efficacy in the treatment of acne vulgaris. It works by exhibiting a phototoxic effect on the heme metabolism of Propionibacterium acnes. Previous studies using blue light showed more improvement in inflammatory lesions than in comedones, as well as some improvement on the untreated side. Cytokines have demonstrated a critical role in the development of inflammation. The expression of pro-inflammatory cytokines such as IL-1[alpha] have been shown to result in the expression of vascular and dermal adhesion molecules, the chemoat-traction of inflammatory cells, and the stimulation of ...

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