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Article: Fortifying AD therapy rationale: it's in the genes.(Dermatologic Therapy)
- Article from:
- Skin & Allergy News
- Article date:
- October 1, 2005
- Author:
CopyrightCOPYRIGHT 2005 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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GLASGOW, SCOTLAND -- A rational approach to the treatment of atopic dermatitis is to use calcineurin inhibitors and topical corticosteroids in different therapeutic niches, based on a scientific understanding of the effects of the drugs on the stratum corneum and a recognition of the associated genetic-environmental interplay, Michael J. Cork, M.B., said at the annual meeting of the British Association of Dermatologists.
Topical corticosteroids, particularly the potent ones, have profound thinning effects on not only the dermis, but also the epidermis, including the stratum corneum. In areas such as the face where the stratum corneum is normally thinner than on ...