Article: SHIRE PLC - Shire Announces NDA Submission Guanfacine for ADHD.

 
SHIRE ANNOUNCES NDA SUBMISSION OF GUANFACINE EXTENDED-RELEASE FOR THE TREATMENT 
OF ADHD IN CHILDREN AND ADOLESCENTS 
 
Shire Seeks FDA Approval of First Selective Alpha-2A-Adrenoceptor Agonist ADHD 
Treatment, Which, if Approved, Broadens the ADHD Portfolio for Shire 
 
 
Basingstoke, UK and Philadelphia, US - August 24, 2006 - Shire plc (LSE: SHP, 
NASDAQ: SHPGY, TSX: SHQ) announced today that it has submitted a new drug 
application (NDA) to the U.S. Food and Drug Administration (FDA) for its 
investigational compound guanfacine extended release (previously referred to as 
SPD503), which, if approved, would be the first once-daily selective 
alpha-2A-adrenoceptor agonist for the ...

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