Article: After Knocking Out Genes, Rye Grass Pollen Made Sneeze-Free.

By Nuala Moran

BioWorld International Correspondent

MELBOURNE, Australia - A number of companies have tried and failed to devise ways of preventing hay fever and allergic asthma by halting the immune cascade initiated when sufferers breathe in pollen. Further products are in development currently.

Now Australian plant scientists have applied lateral thinking to the problem and come up with a way of stopping hay fever at the source - by rendering pollen non-allergenic. They have achieved that by knocking out the genes for two proteins, Lolp-1 and Lolp-2, which are the main culprits in rye grass pollen. Pollen from the modified plants fails to ...

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