Article: First depression patch approved.(Emsam from Bristol-Myers Squibb Co. approved)(Brief article)

The FDA has approved the first skin (transdermal) patch, called Emsam (selegiline), for treating major depression.

Emsam is a once-a-day patch that delivers selegiline, a monoamine oxidase inhibitor, or MAOI, through the skin and into the bloodstream. Its three layers consist of a backing, adhesive drug layer, and release liner that is placed against the skin.

"Emsam provides a significant advance," says Steven Galson, M.D., director of the FDA's Center for Drug Evaluation and Research, "because at least in its lowest dose, patients can use the drug without the usual dietary restrictions associated with these types of drugs known as MAO inhibitors." The ...

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