Article: In RLS, depression severity key when treating both.(Mental Health)

SALT LAKE CITY -- Depression severity is a key factor in determining how to treat comorbid depression and restless legs syndrome, Dr. John Winkelman said at the annual meeting of the Associated Professional Sleep Societies.

The two conditions frequently occur together, and often it is unclear which is primary. Further complicating the matter of treatment is the fact that therapies for the two can be conflicting; for example, SSRIs frequently used to treat depression have been shown to exacerbate RLS symptoms, said Dr. Winkelman, associate director of the Sleep Disorders Program at Brigham and Women's Hospital, Boston.

But the substantial morbidity and ...

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