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Article: Scrub typhus in Himalayas.
- Article from:
- Emerging Infectious Diseases
- Article date:
- October 1, 2006
- Author:
CopyrightCOPYRIGHT 2006 U.S. National Center for Infectious Diseases. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Himachal Pradesh state of India is situated in the outer Himalayan ranges. During the rainy season, several cases of acute febrile illness of unknown origin occurred. Orientia tsutsugamushi was identified as the causative agent by microimmunofluorescence and PCR. Two new genotypes of O. tsutsuqamushi were identified in the reqion.
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Microimmunofluorescence (MIF) assay is the test of choice to diagnose rickettsial diseases (1,2), but more sensitive serologic tests and real-time quantitative PCR are expected to increase the number of cases diagnosed (3). Rickettsial diseases have been reported from various regions of India in the recent past ...