Article: The circadian body temperature rhythm in the elderly: effect of single daily melatonin dosing.(Recently Published Abstracts)(Author abstract)

Gubin DG, Gubin GD, Waterhouse J, Weinert D. Chronobiol Int 2006;23:639-658.

The present study is part of a more extensive investigation dedicated to the study and treatment of age-dependent changes/disturbances in the circadian system in humans. It was performed in the Tyumen Elderly Veteran House and included 97 subjects of both genders, ranging from 63 to 91 yrs of age. They lived a self-chosen sleep-wake regimen to suit their personal convenience. The experiment lasted 3 wks. After 1 control week, part of the group (n=63) received 1.5 mg melatonin (Melaxen) daily at 22:30 h for 2 wks. The other 34 subjects were given placebo. Axillary temperature was measured ...

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