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Article: FDA warns ibuprofen may block aspirin's cardioprotection.(Food and Drug Administration)
- Article from:
- Family Practice News
- Article date:
- October 15, 2006
- Author:
CopyrightCOPYRIGHT 2006 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Concomitant use of low-dose aspirin and ibuprofen may interfere with aspirin's antiplatelet effects, possibly attenuating its cardioprotective benefits, according to a recent statement by the Food and Drug Administration's arm responsible for compiling adverse drug events.
"Platelet function tests suggest there is a pharmacodynamic interaction between 400 mg of ibuprofen and low-dose aspirin when they are dosed concomitantly," the FDA wrote in a statement posted on its MedWatch Web site in September.
Experts stress, however, that virtually all nonsteroidal anti-inflammatory drugs have the potential to interfere with aspirin's cardioprotective effects. ...