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Article: Breast cancer risk and immune responses in healthy women.(Clinical report)
- Article from:
- Oncology Nursing Forum
- Article date:
- November 1, 2006
- Author:
CopyrightCOPYRIGHT 2006 Oncology Nursing Society. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Purpose/Objectives: To summarize the findings of objective and subjective breast cancer risk assessments and their association with psychological distress and immune responses in healthy women with a family history of breast cancer.
Data Sources: Published articles and book chapters.
Data Synthesis: Healthy women with a family history of breast cancer have shown decreased immune responses (i.e., low natural killer cell activity and low Th1 cytokine production), exaggerated biophysiologic reactivity to stimuli, and increased psychological distress.
Conclusions: Objective and subjective breast cancer risk is associated with impaired immune ...