Article: Penn Researchers Discover Initial Steps in Development of Taste; Wnt Protein Required for Taste Buds and Wiring of Taste Signals to Brain.

Byline: University of Pennsylvania Health System

PHILADELPHIA, Dec. 6 (AScribe Newswire) -- Of the five senses, taste is one of the least understood, but now researchers at the University of Pennsylvania School of Medicine have come one step closer to understanding how the sense of taste develops. They have pinpointed a molecular pathway that regulates the development of taste buds. Using genetically engineered mice, they discovered that a signaling pathway activated by small proteins called Wnts is required for initiating taste-bud formation. They have also determined that Wnt proteins are required for hooking up the wiring of taste signals to the brain.

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