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Article: PFA-100 platelet function analyzer.(Answering your questions)
- Article from:
- Medical Laboratory Observer
- Article date:
- November 1, 2006
- Author:
CopyrightCOPYRIGHT 2006 Nelson Publishing. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Q What is the Dade Behring PFA-100 platelet function analyzer? What does it measure? What if the patient is on anti-platelet drugs? What is its application in head trauma injury?
A The Dade Behring PFA-100 platelet function analyzer is used to evaluate primary hemostasis in citrated whole blood. It measures ex vivo platelet binding to collagen/epinephrine (CEPI) or collagen/adenosine diphosphate (CADP). It contains a high-shear flow system to allow blood to pass through a membrane with an aperture. The membrane is coated with collagen fibrils and one of activators epinephrine or ADP (adenosine diphosphate). The platelet activation occurs as blood flows through the ...