Article: Nastech Reports Positive PYY Nasal Spray Clinical Trial Data and Will Advance Obesity Clinical Program in 2007.

Trial Demonstrates Both Intravenous and PYY Nasal Spray Produce Satiety and Calorie Reduction

BOTHELL, Wash., Dec. 21 /PRNewswire-FirstCall/ -- Nastech Pharmaceutical Company Inc. today reported positive results from a dose ranging study designed to evaluate the pharmacokinetic parameters, appetite, food intake and safety of various doses of Nastech's proprietary PYY(3-36) nasal spray in obese subjects. The study identified doses for a long-term Phase 2 efficacy and safety clinical trial.

The study was a double blind, cross-over clinical trial of multiple doses of PYY(3-36) nasal spray in 24 obese subjects with a Body Mass Index of 30-40 kg/m(2). The ...

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