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Article: Hepatitis, meningitis and hydrocephalus caused by herpes simplex virus type I.
- Article from:
- American Journal of Infectious Diseases
- Article date:
- January 1, 2006
- Author:
CopyrightCOPYRIGHT 2006 Science Publications. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Abstract: Herpes simplex virus type is the most frequent cause of sporadic and severe encephalitis in western countries. We report the exceptional case of an immunocompetent man aged 51 and who presented with hepatitis and meningitis by herpes simplex virus. Encephalitis responded to acyclovir but hepatitis did not. The patient developed diffuse hydrocephalus that required the appropriate shunt 20 days after being asymptomatic. Several aspects deserve discussion: the clinical onset with meningeal syndrome, the value of the PCR technique for diagnosis and follow-up purposes, the magnetic resonance (MRI) findings, the anicteric hepatitis with reversible cytolysis and ...