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Article: PCB exposure affects antibody response in vaccinated children.(Immunity)
- Article from:
- Environmental Health Perspectives
- Article date:
- January 1, 2007
- Author:
CopyrightCOPYRIGHT 2007 National Institute of Environmental Health Sciences. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Heilmann C, Grandjean P, Weihe P, Nielsen F, Budtz-Jorgensen E. 2006. Reduced antibody responses to vaccinations in children exposed to polychlorinated biphenyls. PLoS Med 3(8):e311.
Although children are known to display varied antibody responses to vaccination, little is known about the causes of these variations. One possibility is that persistent organochlorine pollutants such as polychlorinated biphenyls (PCBs) elicit immunotoxic effects that influence the production of specific antibodies. In this report, NIEHS grantee Philippe Grandjean of the Harvard School of Public Health and his colleagues confirm an association between increased PCB exposure and ...