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Article: Synthesis and characterization of a series of novel phenol- and polyphenol-based glycerolipids (1).
- Article from:
- Canadian Journal of Chemistry
- Article date:
- October 1, 2006
- Author:
CopyrightCOPYRIGHT 2006 NRC Research Press. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Abstract: A building block approach was used to design a modular synthetic route for the preparation of novel glycerolipids with phenolic and polyphenolic headgroups. Based on this scheme, it is possible to vary the substitution pattern of the headgroup, the stereochemistry of the backbone, and the length of the sidechains. Five glycerolipids with different headgroups and identical backbone stereochemistry and chain length have been prepared.
Key words: glycerolipid, polyphenol, hydrogen bonding, lipid-protein interaction, self-adhering.
Resume : On a developpe une methode modulaire de synthese de nouveaux glycerolipides comportant des tetes phenoliques ...