Article: Population-based laboratory surveillance for AmpC [beta]-lactamase-producing Escherichia coli, Calgary.(RESEARCH)(ampicillin)(Clinical report)

In the Calgary Health Region during 2000-2003, prospective, active, population-based laboratory surveillance for all cefoxitin-resistant Escherichia coli isolates was performed. Isolates were screened with an inhibitor-based disk test, and plasmid-mediated types were identified by multiplex PCR with sequencing. A total of 369 AmpC [beta]-lactamase-producing E. coil isolates were identified; annual incidence rates were 1.7, 4.3, 11.2, and 15 per 100,000 residents for each year, respectively. AmpC [beta]-lactamase-producing E. coli was 5x more likely to be isolated from female than male patients across all age groups except

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