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Article: Hyperglycemia and mortality in elderly patients with Staphylococcus aureus bacteremia.(Clinical report)
- Article from:
- Southern Medical Journal
- Article date:
- March 1, 2007
- Author:
CopyrightCOPYRIGHT 2007 Southern Medical Association. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Objective: To investigate the association between hyperglycemia and in-hospital mortality in elderly patients with Staphylococcus aureus bacteremia (SAB).
Methods: We reviewed the medical records of 135 elderly patients with SAB admitted to two tertiary medical centers from January 2003 until December 2004. Patients were stratified into two groups: those with a 7-day post-SAB mean blood glucose
Results: Seventy-four (54.8%) patients had methicillin-resistant Staphylococcus aureus bacteremia. During the follow-up period from admission until discharge, 36 (26.7%) patients died. Twenty-one (21.4%) of 98 patients with a 7-day post-SAB mean blood glucose
<170 mg/dL died, while 15 (40.5%) of 37 patients with a 7-day post-SAB mean blood glucose [greater than or equal to]170 mg/dL expired. Multivariate analysis identified 3 independent determinants of death: Simplified Acute Physiology Score (SAPS) score at onset of SAB>45 (OR 5.3, ...