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Article: Identification of women with an increased risk of developing radiation-induced breast cancer: a case only study.(Research article)
- Article from:
- Breast Cancer Research (Online Edition)
- Article date:
- April 11, 2007
- Author:
CopyrightCOPYRIGHT 2007 BioMed Central Ltd. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Authors: Annegien Broeks [1]; Linde M Braaf [1]; Angelina Huseinovic [1]; Anke Nooijen [1]; Jos Urbanus [1]; Frans BL Hogervorst [2]; Marjanka K Schmidt [3]; Jan GM Klijn [4]; Nicola S Russell [5]; Flora E Van Leeuwen [3]; Laura J Van 't Veer (corresponding author) [1,2]
Introduction
Several risk factors for the development of breast cancer, such as family history, reproductive factors and exposure to radiation, have been identified. Out of all breast cancers, 5 to 10% can be attributed to germline mutations in familial high-risk genes such as
BRCA1
or
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