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Article: Perineurioma: a distinctive and underrecognized peripheral nerve sheath neoplasm.(Disease/Disorder overview)
- Article from:
- Archives of Pathology & Laboratory Medicine
- Article date:
- April 1, 2007
- Author:
CopyrightCOPYRIGHT 2007 College of American Pathologists. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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* Context.--Perineuriomas are benign peripheral nerve sheath neoplasms composed of perineurial cells with characteristic immunohistochemical and ultrastructural features. They have been traditionally classified into two main types according to their location--intraneural and extraneural--and overlap histologically with many other tumors, which may be diagnostically challenging to general surgical pathologists.
Objective.--To review the clinical, morphologic, immunohistochemical, ultrastructural, cytogenetic, and molecular genetic aspects of perineurioma, as well as to discuss its clinicopathologic variants and differential diagnosis.
Data ...