Article: Treatment of polycystic ovary syndrome with spironolactone plus licorice.(Recent Abstracts)(Brief article)(Clinical report)

Armanini D, Castello R, Scaroni C, et al. Eur J Obstet Gynecol Reprod Biol 2006 Nov 16; [Epub ahead of print]

OBJECTIVE: The aim of the study was to compare the effect of spironolactone (antagonist of mineralocorticoid and androgen receptors) versus spironolactone plus licorice (agonist of mineralocorticoid receptors and mild inhibitor of androgen synthesis) on plasma renin activity, aldosterone and androgen levels in women with polycystic ovary syndrome (PCOS). STUDY DESIGN: Thirty-two women with PCOS were divided into two groups: 16 received 100mg spironolactone and 16 spironolactone plus 3.5g of licorice a day. Blood pressure, body mass index, serum ...

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