Article: Picoplatin: Poniard's next big thing in platinum therapies?(Lung Cancer Phase III Begins)(Clinical report)

Non-small-cell lung cancer gets most of the press, but the less common, small-cell tumors strike in about 25 percent of cases--and could provide an entry to the market followed by handsome revenues for the likes of Poniard Pharmaceuticals Inc. and would-be competitor Pharmion Corp.

At the start of the month, Poniard kicked off a pivotal Phase III trial testing picoplatin in SCLC called SPEAR (Study of Picoplatin Efficacy After Relapse), conducted under a special protocol assessment agreement with the FDA. The randomized, controlled study is enrolling about 400 patients who are refractory to--or who have progressed within six months of completing--treatment with ...

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