Article: TOPOTARGET UNVEILS AVUGANE PHASE II TRIAL FOR ACNE VULGARIS.(Clinical report)

TopoTarget A/S (CSE: TOPO), Copenhagen, Denmark, has announced that a Phase II clinical trial has been initiated, testing Avugane, a topical valproic acid - an HDAC inhibitor drug - in the treatment of acne vulgaris. This double-blind, randomised Phase II study comprises four trial arms, testing three different dose strengths of Avugane compared to a placebo control group. The trial follows the positive results with Avugane as previously announced.

This new Phase II study will investigate the efficacy and safety in a four-armed trial with three different dose strengths of topically applied Avugane in the treatment of mild to moderate acne vulgaris in comparison ...

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