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Article: Delayed presentation of impending necrosis following soft tissue augmentation with hyaluronic acid and successful management with hyaluronidase.(CASE REPORTS)(Clinical report)
- Article from:
- Journal of Drugs in Dermatology
- Article date:
- March 1, 2007
- Author:
CopyrightCOPYRIGHT 2007 Journal of Drugs in Dermatology, Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Abstract
Soft tissue augmentation is a key element in the successful management of facial rhytids and scars. Injection of hyaluronic acid gels into the dermis is generally well-tolerated with only minimal side effects. Injection necrosis is a rare but clinically significant side effect. (1,2) We present a case of what appears to be slow swelling after injection of Juvederm[TM] (Allergan, Irvine, CA), which yielded delayed compression and vascular occlusion resulting in cutaneous necrosis. Such vascular compromise can present as delayed rather than immediately upon injection as would be the case with similarly reported cases of intra-arterial injection.
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