Article: Phase III Study Shows Avastin Plus Interferon Therapy Nearly Doubled Median Progression-Free Survival in Patients With Previously Untreated Advanced Kidney Cancer.(Clinical report)

- First Antibody That Specifically Inhibits VEGF to Show Improvement in a Phase III Kidney Cancer Trial -

CHICAGO -- Genentech, Inc. (NYSE:DNA) today announced that a Roche-sponsored, randomized placebo-controlled Phase III clinical study of Avastin([R]) (bevacizumab) in combination with interferon alfa-2a therapy increased the median time patients with first-line metastatic renal cell carcinoma (mRCC) lived without their cancer growing or spreading as defined by progression-free survival (PFS). Patients receiving Avastin plus interferon alfa-2a therapy experienced a 59 percent improvement in PFS (based on a hazard ratio of 0.63) compared to those receiving ...

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