Article: Sexually transmitted infection management, safer sex promotion and voluntary HIV counselling and testing in the male circumcision trial, Rakai, Uganda.(ROUNDTABLE)(Clinical report)

RECENT randomised clinical trials on the efficacy of male circumcision show that medically performed adult male circumcision can be safe and efficacious in reducing the sexual transmission of HIV from HIV-infected women to their HIV-uninfected male partners. (1-3) In addition, a stochastic simulation model of the impact of male circumcision on HIV incidence and cost per infection averted, using empirically derived parameters from a cohort in Rakai, Uganda, suggests that male circumcision could have substantial impact on the HIV epidemic and provide a cost-effective prevention strategy, if benefits are not countered by behavioural disinhibition. (4) A recent WH0/ UNAIDS ...

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