Article: For girls on risperidone, don't measure prolactin.(Child/Adolescent Psychiatry)

NEW YORK -- A 6-year-old girl with autism is treated with risperidone 0.5 mg twice daily, and after 2 months of treatment her behavior is improved, and there are no noted side effects. But her serum prolactin is clearly elevated for her age at 45 ng/mL. What should you do?

Nothing. In fact, her serum prolactin shouldn't have been measured in the first place, Dr. Harold E. Carlson said at a psychopharmacology update sponsored by the American Academy of Child and Adolescent Psychiatry.

Secretion of prolactin is primarily regulated by tonic inhibition by dopamine, which is secreted by the hypothalamus and acts on D2 dopamine (DA) receptors in the pituitary ...

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