Article: Herpes simplex infection increases HIV risk for men who have sex with men.(DIGESTS)(human immunodeficiency virus)(Author abstract)

In a randomized, controlled study of an HIV prevention intervention conducted among high-risk men who have sex with men, HIV infection rates were elevated among those who acquired herpes simplex virus type 2 (HSV-2) during follow-up, particularly within six months of the herpes diagnosis. (1) The risk of herpes, in turn, was elevated among black men and among men who engaged in certain risky behaviors; it was not reduced among those who participated in the intervention.

The study, which was carried out in six U.S. cities from 1999 to 2003, recruited HIV-negative men who were at least 16 years old, had had anal sex with a man in the year before enrollment and were ...

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