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Article: A new approach to comparing efficacy results from clinical trials of topical acne vulgaris treatments.
- Article from:
- Journal of Drugs in Dermatology
- Article date:
- July 1, 2007
- Author:
CopyrightCOPYRIGHT 2007 Journal of Drugs in Dermatology, Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Abstract
Clinicians must evaluate a voluminous amount of information from clinical trials when choosing among the growing number of topical acne treatments. This article describes a simple way to evaluate and broadly compare the efficacy results of well-controlled phase III clinical trials of topical acne treatments by taking into account the placebo effect (or active control effect). Key efficacy results are drawn from the package inserts of 7 primary topical acne treatments. To account for placebo effect, the mean percent reduction with placebo was subtracted from that of the active treatment for each type of lesion and also calculated as an average of these ...
Related newspaper, magazine, and journal articles:
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Article: Topical acne medication. (Products).
OB GYN News;
November 1, 2001 ;
294 words
...Vanoxide-HC (benzoyl peroxide 5% and hydrocortisone .05%) is a topical, water-based lotion for the treatment of acne. The benzoyl peroxide in the lotion dries the affected area and prevents the growth of bacteria, while the hydrocortisone fights inflammation and redness that often occurs with acne.
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