Article: Spatial and temporal variation in [PM.sub.2.5] chemical Composition in the United States for health effects studies.

BACKGROUND: Although numerous studies have demonstrated links between particulate matter (PM) and adverse health effects, the chemical components of the PM mixture that cause injury are unknown.

OBJECTIVES: This work characterizes spatial and temporal variability of [PM.sub.2.5] (PM with aerodynamic diameter $lt 2.5 [micro]m) components in the United States; our objective is to identify components for assessment in epidemiologic studies.

METHODS: We constructed a database of 52 [PM.sub.2.5] component concentrations for 187 U.S. counties for 2000-2005. First, we describe the challenges inherent to analysis of a national [PM.sub.2.5] chemical composition ...

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