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Article: New steroid for countering allergic rhinitis.(New drug information from the publishers of MPR)(Drug overview)
- Article from:
- Clinical Advisor
- Article date:
- July 1, 2007
CopyrightCOPYRIGHT 2007 Haymarket Media, Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Product: Veramyst
Company: GlaxoSmithKline
Pharmacologic class: Corticosteroid
Active ingredient: Fluticasone furoate 27.5 [micro]g/spray; alcohol-free.
Indication: Seasonal and perennial allergic rhinitis.
Pharmacology: Fluticasone furoate is a synthetic trifluorinated corticosteroid with potent antiinflammatory activity. The exact mechanism by which this corticosteroid exerts its effects in the treatment of allergic rhinitis is unknown. Corticosteroids have a wide range of actions on multiple cell types (e.g., mast cells, eosinophils, neutrophils, macrophages, lymphocytes) and mediators (e.g., histamine, eicosanoids, ...