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Article: Targeting HER-2/neu in early breast cancer development using dendritic cells with staged interleukin-12 burst secretion.
- Article from:
- Advances in Breast Cancer
- Article date:
- June 1, 2007
- Author:
CopyrightCOPYRIGHT 2007 Mediscript Ltd. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Targeting HER-2/neu in early breast cancer development using dendritic cells with staged interleukin-12 burst secretion
Czerniecki BJ, Koski GK, Koldovsky U et al.
Cancer Research, 2007, 67, 1842-1852
This paper reports an extremely interesting approach to the management of early changes in breast cancer such as HER-2/neu-over-expressing ductal carcinoma in situ (DCIS). The authors have presented the highly interesting and preliminary results of a trial in 13 patients with DCIS. The strategy was focused on the HER-2/neu-expressing DCIS because of the frequent association with recurrent disease and of course the availability of both major ...