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Consider neuromuscular disorders in association with noncompaction.(Letter to the editor)

To the Editor: With interest, we read the article by Fox et al (1) on a 29-year-old African-American female in whom left ventricular hypertrabeculation (LVHT), also known as noncompaction, was detected upon investigation for heart failure from dilative cardiomyopathy. The presentation raises the following concerns:

LVHT is presented as an exclusively congenital abnormality. In rare cases, however, LVHT can develop during one's lifespan, as confirmed by previous echocardiograms without LVHT. (2) All of these patients suffered from a neuromuscular disorder (NMD). In these patients, LVHT may represent the attempt to compensate for the failing myocardium. (2) No systematic ...

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