Article: Melatonin for sleep disorders.

Bandolier 82 looked at a good, large, randomised trial of melatonin for jet lag and found it not to be effective for sleep problems. Of course, melatonin may still have been useful for other sleep disturbances, though one would have had to be an enthusiast to bet on it. We now have two systematic reviews [1,2] to demonstrate that being a bit suspicious was probably the correct approach.

Searching

These linked reviews had a heroic searching strategy, covering electronic searching of more databases than most of us knew existed, plus bibliographies and some hand searching. The latest searches were in early 2004. For inclusion, studies had to be randomised ...

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