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Coenzyme Q10 and statin myopathy.
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Bandolier
- Article date:
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July 1, 2007
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Copyright informationCOPYRIGHT 2007 Bandolier Ltd. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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For some time there has been a view that the muscle pains associated with statins may be reversed by taking coenzyme Q10. The argument is that statins inhibit the biosynthesis of both cholesterol and ubiquinone (fancy name for coenzyme Q10), with resultant lowering of cholesterol and ubiquinone in blood, ubiquinone in muscle, and, as ubiquinone is involved in electron transport and ATP formation, fatigue and muscle pain.
Whether taking coenzyme Q10 helps overcome that muscle pain is another matter, but there are a few straws in the wind.
Systematic review
A systematic review [1] sought all the evidence linking coenzyme Q10 with statin-associated myopathy, ...
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coenzyme Q
A Dictionary of Chemistry;
4 words
...coenzyme Q See ubiquinone .
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Coenzyme Q10.(COMPLEMENTARY AND ALTERNATIVE MEDICINE)
American Family Physician;
September 15, 2005 ;
Bonakdar, Robert Alan Guarneri, Erminia;
787 words
...Coenzyme Q10 is a vitamin-like substance used in the treatment...and oxidative injury. Studies supporting the efficacy of coenzyme Q10 appear most promising for neurodegenerative disorders...Parkinson's disease and certain encephalomyopathies for which coenzyme Q10 has gained orphan drug status. Results in ...
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Popular Dietary Supplement Coenzyme Q Shortens Life Span of Worms...
Ascribe Higher Education News Service;
January 4, 2002 ;
682 words
......Newswire) -- A popular dietary supplement, Coenzyme Q, accelerates aging and death in a microscopic...biochemists. Adult worms on a diet without Coenzyme Q live 60 percent longer than those on...Our research indicates that too much Coenzyme Q for adults can be harmful, said Clarke...
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WHAT IS . . . COENZYME Q10?
The Sunday Herald;
July 3, 2005 ;
200 words
...Discovered in 1957, Coenzyme Q10, or simply CoQ10, is a nutrient that...Researchers have explored the effects of coenzyme Q10 in people with periodontal disease, which has been linked to coenzyme Q10 deficiency. Studies have shown people...
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Ubisol-Aqua(TM): Coenzyme Q10 May Prevent Toxicity of HIV Drug Therapy.
PR Newswire;
July 26, 2007 ;
662 words
......Zymes' new water-soluble formulation of coenzyme Q10 increases growth and survival of...studied the safety and effectiveness of coenzyme Q10 in reducing the neurological toxicity...treatment of patients with nutrients such as coenzyme Q10 has shown promise in the prevention...
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THE CONFUSION OVER COENZYME A.
Health Products Business;
June 1, 2000 ;
Schauss, Alexander G.;
787 words
......supplements manufacturer asked me what I thought of adding coenzyme A to a supplement formula. I thought that a strange...about this substance is probably widepsread. WHAT IS COENZYME A? Coenzyme A has many functions in the human body. It is involved...
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Coenzyme Q10 for migraine prophylaxis.(ALTERNATIVE MEDICINE)
Internal Medicine News;
March 1, 2006 ;
Walsh, Nancy;
787 words
...History and Rationale for Use Coenzyme Q10 is a naturally occurring hydrophobic...c (Cephalalgia 2002;22:137-41). As such, coenzyme Q10 is essential for cellular energy metabolism. The coenzyme was first isolated in 1957 from bovine heart...
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Coenzyme Q10 for migraine prophylaxis.(care and treatment)
Clinical Psychiatry News;
March 1, 2006 ;
Walsh, Nancy;
787 words
...History and Rationale for Use Coenzyme Q10 is a naturally occurring hydrophobic...c (Cephalalgia 2002;22:137-41). As such, coenzyme Q10 is essential for cellular energy metabolism. The coenzyme was first isolated in 1957 from bovine heart...
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Another use of coenzyme Q10: migraine prevention.(Abstracts of...
Original Internist;
September 1, 2004 ;
Maurer, Richard;
246 words
......times per month, were given 150 mg of coenzyme Q10 each morning at breakfast for a period...adverse events were associated with the coenzyme Q10 therapy. Ninety three percent of...indicating longer treatment might be required. Coenzyme Q10 has been shown to improve mitochondrial...
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"Jack of all nutrients": Coenzyme Q10
Better Nutrition;
August 1, 1996 ;
Scheer, James F;
787 words
......doctor telling a skeptical listener that coenzyme Q10 is helpful in revving up energy...the aging process. "Is there anything coenzyme Q10 can't do?" asked the skeptic. "About...listener. However, the versatility of coenzyme Q10 (also reffered to as CoQ1O) is anything...
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Does coenzyme Q{-1}{-0} help combat problems like hypertension or cancer?
The Boston Globe;
August 18, 2008 ;
JUDY FOREMAN;
294 words
...Coenzyme Q{-1}{-0} is a fat-soluble, vitamin-like substance that...California, Irvine. Scientists are increasingly interested in coenzyme Q{-1}{-0} because there's growing recognition of the...diabetes, obesity, heart problems, and autism, said Wallace. CoenzymeQ{-1}{-0} is plentiful in foods including ...
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Restricted uptake of dietary coenzyme Q is in contrast to the unrestricted...
The Journal of Nutrition;
September 1, 1996 ;
Zhang, Yiyi; Turunen, Mikael; Appelkvist, Eeva-Liisa;
787 words
...Restricted Uptake of Dietary Coenzyme Q Is in Contrast to the Unrestricted...dietary uptake of alpha-tocopherol and coenzyme Q was investigated in rats. Rats...supplemented with a-tocopherol or coenzyme Q^sub 10^ ( 1 g/kg diet) or an unsupplemented...
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Pilot study: coenzyme [Q.sub.10] relieved statin-induced...
Family Practice News;
June 1, 2005 ;
406 words
...Orlando, Fla, -- Coenzyme [Q.sub.10] markedly improved statin-induc...vitamin E (control group) or 100 mg coenzyme [Q.sub.10] daily for 30 days. On a...mean of 6.2 to 3.1 in the group taking coenzyme [Q.sub.10] but remained unchanged in...
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High bioavailability for SoluTM Q10 from BASF; Scientific study confirms...
M2 Presswire;
January 23, 2007 ;
528 words
......confirms outstanding performance of BASF's coenzyme Q10; Customers benefit from easy processing...Q10 to several commercially obtainable coenzyme Q10 formulations. Bioavailability is...indicating how rapidly and completely the coenzyme is absorbed by the body, and depends...
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Coenzyme [Q.sub.10] eased statin-induced muscle pain.(Cardiovascular...
Internal Medicine News;
June 1, 2005 ;
Jancin, Bruce;
285 words
...ORLANDO, FLA. -- Coenzyme [Q.sub.10] markedly reduced statin...vitamin E (control group) or 100 mg coenzyme [Q.sub.10] daily for 30 days. On a...mean of 6.2 to 3.1 in the group taking coenzyme [Q.sub.10] but was unchanged in controls...
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