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Article: Preventing colorectal adenomas.
- Article from:
- Bandolier
- Article date:
- November 1, 2006
CopyrightCOPYRIGHT 2006 Bandolier Ltd. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Bandolier 129 had a quick review of trials of aspirin, coxibs, and NSAIDs to prevent polyp recurrence in familial polyposis or prevention of adenomas. In familial polyposis there was some evidence that coxibs and NSAIDs may prevent polyp recurrence, but trials tended to be small and short. Three trials of low dose aspirin to prevent colorectal adenomas were longer (2.5 to 4 years) and larger (about 2,000 patients in total), and tended to show some reduction in adenoma formation, by about 10%.
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