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Article: The positive T wave.(Original Investigation)(Report)
- Article from:
- The Anatolian Journal of Cardiology (Anadolu Kardiyoloji Dergisi)
- Article date:
- July 1, 2007
- Author:
CopyrightCOPYRIGHT 2007 Galenos Yayincilik. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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ABSTRACT
Objective: The instant of maximum slope (Tup) of the T wave in the unipolar electrogram is a well-established measure of repolarisation time (TR). Nevertheless, recent observations on positive T waves have caused a renewed debate. The purpose of this study was to elucidate the mechanism that leads to positive and negative T waves and to investigate which electrogram feature best predicts TR.
Methods: We simulated propagating action potentials (AP) and electrograms with a bidomain reaction-diffusion model of the human heart including heterogeneous ion-channel properties. To explain positive T waves we compared results with those of a much simpler ...