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Article: Effect of varying frequency and duration of electroacupuncture stimulation on carrageenan-induced hyperalgesia.(Papers)(Clinical report)
- Article from:
- Acupuncture in Medicine
- Article date:
- July 1, 2007
- Author:
CopyrightCOPYRIGHT 2007 British Medical Acupuncture Society. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Abstract
Objective Although electroacupuncture (EA) therapy is used to relieve various kinds of pain, the optimal frequency and duration of EA remain unclear. We investigated the effect of varying frequency and duration of EA during hyperalgesia elicited by carrageenan-induced inflammation.
Methods Carrageenan was administered by subcutaneous intraplantar injection to induce inflammation. Nociceptive thresholds were measured using the paw pressure threshold (PPT) (Randall-Selitto Test). EA was applied at 3, 15, or 100Hz to the left anterior tibial muscles for 1, 15, or 60 minutes. Intensities used were chosen within the known tolerance of the animal, ...