Article: Route of administration for erythropoiesis-stimulating agents: patient and nursing considerations.(Sponsored Educational Supplement)

EPoetin alfa is typically administered by the intravenous (IV) route for patients on hemodialysis and by the subcutaneous (SC) route for patients on peritoneal dialysis. Using the IV route for patients on hemodialysis avoids the need for additional needle sticks, enhances patient comfort, and provides a staff-convenient thrice-weekly dosing schedule. In addition, the Epoetin alfa prescribing information that has been approved by the Food and Drug Administration recommends the IV route for patients on hemodialysis due to the warning of an increased risk of pure red cell aplasia associated with SC administration. Conversely, SC administration is more convenient for patients ...

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