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Article: Radiotherapy averts progression after radical prostatectomy.(Urology)(Clinical report)
- Article from:
- Internal Medicine News
- Article date:
- August 15, 2007
- Author:
CopyrightCOPYRIGHT 2007 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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CHICAGO -- Adjuvant radiotherapy after radical prostatectomy significantly reduced biochemical progression for men with pT3 prostate cancer in a multicenter phase III trial conducted in Germany
The 385-patient study showed progression-free survival rates of 55% for men randomized to adjuvant radiotherapy versus 44% for those who were assigned to "watchful waiting" after surgery.
This gap widened when 78 patients dropped out of the study in a planned exclusion because they did not reach undetectable prostate-specific antigen (PSA) levels. An intent-to-treat analysis of the remaining 307 men showed biochemical control reached 72% with adjuvant radiotherapy ...