Article: Radiotherapy averts progression after radical prostatectomy.(Urology)(Clinical report)

CHICAGO -- Adjuvant radiotherapy after radical prostatectomy significantly reduced biochemical progression for men with pT3 prostate cancer in a multicenter phase III trial conducted in Germany

The 385-patient study showed progression-free survival rates of 55% for men randomized to adjuvant radiotherapy versus 44% for those who were assigned to "watchful waiting" after surgery.

This gap widened when 78 patients dropped out of the study in a planned exclusion because they did not reach undetectable prostate-specific antigen (PSA) levels. An intent-to-treat analysis of the remaining 307 men showed biochemical control reached 72% with adjuvant radiotherapy ...

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