Article: 40 mg of lisinopril daily is ideal for diabetic nephropathy.(Metabolic Disorders)

AMSTERDAM -- In type 1 diabetic patients with diabetic nephropathy, 40 mg/day of lisinoprll appears to be the ideal dose for renoprotection, Dr. Katrine J. Schjoedt said in a poster presentation at the annual meeting of the European Association for the Study of Diabetes.

Angiotensin converting enzyme inhibitors such as lisinopril are considered first-line agents for renoprotection in patients with type 1 diabetes who have nephropathy, because these drugs reduce albuminuria in addition to lowering blood pressure. The currently recommended 20 mg/day dose of lisinopril is based on the drug's blood pressure-lowering effect; the optimal dose for renoprotection has not ...

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