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Article: Minocycline-induced hyperpigmentation resolves during oral isotretinoin therapy.(CASE REPORTS)
- Article from:
- Journal of Drugs in Dermatology
- Article date:
- December 1, 2007
- Author:
CopyrightCOPYRIGHT 2007 Journal of Drugs in Dermatology, Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Abstract
Although disfiguring hyperpigmentation is a well-defined complication of minocycline therapy, modalities to reverse the phenomenon are unpredictable. We report a case of minocycline-induced, blue-black pigmentation in a 23-year-old Hispanic man, which resolved after treatment with oral isotretinoin for acne vulgaris.
Introduction
Minocycline is a widely prescribed, broad-spectrum antibiotic for the treatment of acne. Cutaneous hyperpigmentation induced by minocycline is a well-recognized, infrequent adverse effect. (1-18) The pigmentation generally associated with long-term and/or high-dose therapy may persist for years. The Q-switched ...