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Article: Intranasal desmopressin linked to severe hyponatremia, seizures.(NEWS FROM THE FDS)
- Article from:
- Family Practice News
- Article date:
- December 15, 2007
- Author:
CopyrightCOPYRIGHT 2007 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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BY ELIZABETH MECHCATIE Senior Writer Intranasal formulations of desmopressin acetate are no longer indicated for treating primary nocturnal enuresis because of the risk of severe hyponatremia and seizures associated with these products when used for this indication, according to the Food and Drug Administration.
"Doctors should consider other options for managing this condition," because certain patients taking desmopressin are at risk for developing severe hyponatremia that can result in seizures and death, according to an alert issued by the FDA this month.
The FDA reviewed 61 postmarketing reports of hyponatremic-related seizures associated with the ...