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Fish oil improves motor skills in children with phenylketonuria.(Literature Review & Commentary)(Brief article)
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Townsend Letter
- Article date:
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January 1, 2008
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Copyright informationCOPYRIGHT 2008 The Townsend Letter Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Thirty-six patients (aged one to eleven years) with phenylketonuria (PKU) received fish oil (18% eicosapentaenoic acid and 12% docosahexaenoic acid [DHA]), providing DHA at a dose of 15 mg per kg of body weight per day for three months. At baseline, as compared with age-matched controls, PKU patients had low concentrations of omega-3 fatty acids in plasma phospholipids and a poorer mean performance on a measure of body coordination and fine motor skills (Rostock-Oseretzky Scale motor development index, 107 vs. 117; p = 0.01). After supplementation, the mean motor development index increased from 107 at baseline to 115 (p = 0.011), whereas this parameter did not change in the ...
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