Article: Update on overall prevalence of major birth defects--Atlanta, Georgia, 1978-2005.(Report)(Table)

Major structural or genetic birth defects affect approximately 3% of births in the United States, are a major contributor to infant mortality (1,2), and result in billions of dollars in costs for care (3). Although the causes of most major birth defects are unknown, concerns have been raised that certain factors, such as an increase in the prevalence of diabetes among women, might result in increased prevalence of birth defects over time (4). This report updates previously published data from the Metropolitan Atlanta Congenital Defects Program (MACDP), the oldest population-based birth defects surveillance system in the United States with active case ascertainment (5). ...

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