Article: Xencor Receives Patent for its Proprietary Antibody Fc Optimization Technology.

MONROVIA, Calif. -- Xencor, Inc., a company developing protein and antibody therapeutics, announced today that it received a patent from the United States Patent and Trademark Office (US 7,317,091 B1) entitled, "Optimized Fc Variants," expanding on the company's rich patent estate for its proprietary Protein Design Automation[R] technology. This is the first issuance from a series of patent applications covering Xencor's XmAb[TM] antibody Fc engineering technology, which is comprised of a suite of thousands of selectively engineered Fc domains. Xencor's engineered Fc domains have been shown to improve antibody potency against tumor cells by more than 100-fold, ...

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